What Is NAD+ and Why Does It Matter for Aging?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body that plays a critical role in energy production, DNA repair, and cellular metabolism. It’s essential for the function of sirtuins — proteins that regulate aging, inflammation, and stress resistance. The problem is that NAD+ levels decline significantly with age, and this decline is increasingly linked to many of the hallmarks of aging, including reduced energy, cognitive decline, and decreased cellular repair capacity.
NAD+ injection therapy delivers this coenzyme directly into your system at concentrations that oral supplements can’t achieve due to the breakdown that occurs during digestion. By restoring NAD+ levels, the therapy aims to support cellular energy production, enhance cognitive clarity, improve metabolic function, and activate the body’s natural repair mechanisms.
How NAD+ Injection Therapy Works
NAD+ can be administered through intramuscular injection or intravenous infusion, with injection being the faster and more convenient option for most patients. The NAD+ is delivered directly into the body, bypassing the digestive system for maximum bioavailability. Sessions are typically quick — intramuscular injections take just a few minutes, while IV infusions may take one to several hours depending on the protocol.
Most treatment plans involve an initial series of sessions to build NAD+ levels, followed by maintenance sessions to sustain the effects. The specific protocol depends on your health goals, baseline NAD+ status, and how your body responds to treatment. Dr. Berdichevskaya tailors each plan to the individual patient.
Potential Benefits of NAD+ Therapy
Patients and researchers have reported a range of benefits associated with NAD+ therapy, including increased energy and reduced fatigue, improved mental clarity and focus, enhanced athletic recovery, support for healthy aging at the cellular level, improved mood and stress resilience, and potential benefits for metabolic health.
It’s important to approach NAD+ therapy with realistic expectations. While the science behind NAD+’s role in cellular function is well-established, much of the clinical evidence for injectable NAD+ therapy is still emerging. Dr. Berdichevskaya discusses the current evidence honestly during consultation, so you can make an informed decision about whether NAD+ therapy aligns with your wellness goals.
Cost Considerations and What Affects Pricing
NAD+ injection therapy costs vary based on the delivery method (injection vs. IV), the dosage, the number of sessions in your treatment plan, and whether NAD+ is combined with other wellness therapies. During your consultation, Avellina Aesthetics provides transparent pricing and helps you understand what a realistic treatment plan looks like for your goals and budget.
Safety and Side Effects
NAD+ injections are generally well-tolerated. The most common side effects are mild and temporary — including discomfort at the injection site, mild nausea, or warmth and flushing during administration. Serious adverse effects are rare when the therapy is administered by a qualified medical professional using pharmaceutical-grade NAD+.
As with any injection therapy, the safety of NAD+ treatment depends significantly on the provider. At Avellina Aesthetics, all NAD+ treatments are supervised by Dr. Berdichevskaya, who evaluates your health history before starting any protocol and monitors your response throughout treatment.
Ready to Book Your Consultation?
If you’re ready to explore your options or have questions about which treatment is right for you, contact Avellina Aesthetics to schedule a consultation with Dr. Violetta Berdichevskaya. Call us at (215) 722-6022 or visit to get started.